Preoperative assessment of intracranial tumors with perfusion MR and a volumetric interpolated examination: a comparative study with DSA

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Wetzel, Stephan G., Cha, Soonmee, Law, Meng, Johnson, G., Golfinos, John, Lee, Peter and Nelson, Peter Kim (2002) Preoperative assessment of intracranial tumors with perfusion MR and a volumetric interpolated examination: a comparative study with DSA. American Journal of Neuroradiology, 23 (10). pp. 1767-1774. ISSN 1936-959X

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Abstract

BACKGROUND AND PURPOSE: In evaluating intracranial tumors, a safe low-cost alternative that provides information similar to that of digital subtraction angiography (DSA) may be of interest. Our purpose was to determine the utility and limitations of a combined MR protocol in assessing (neo-) vascularity in intracranial tumors and their relation to adjacent vessels and to compare the results with those of DSA. METHODS: Twenty-two consecutive patients with an intracranial tumor who underwent preoperative stereoscopic DSA were examined with contrast-enhanced dynamic T2*-weighted perfusion MR imaging followed by a T1-weighted three-dimensional (3D) MR study (volumetric interpolated brain examination [VIBE]). The maximum relative cerebral blood volume (rCBV) of the tumor was compared with tumor vascularity at DSA. Critical vessel structures were defined in each patient, and VIBE images of these structures were compared with DSA findings. For full exploitation of the 3D data sets, maximum-intensity projection algorithms reconstructed in real time with any desired volume and orientation were used. RESULTS: Tumor blush scores at DSA were significantly correlated with the rCBV measurements (r = 0.75; P

Item Type:	Article
Uncontrolled Keywords:	physiology female humans magnetic resonance angiography male middle aged neurologic examination new york preoperative care recurrence severity of illness index statistics as topic
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Norwich Clinical Trials Unit Faculty of Medicine and Health Sciences > Research Groups > Cancer Studies
Related URLs:	https://www.ajnr.org/content/23/10/1767
Depositing User:	Pure Connector
Date Deposited:	28 Sep 2015 13:48
Last Modified:	14 Aug 2023 11:31
URI:	https://ueaeprints.uea.ac.uk/id/eprint/54438
DOI:

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