Treatment-related change versus tumor recurrence in high-grade gliomas: a diagnostic conundrum--use of dynamic susceptibility contrast-enhanced (DSC) perfusion MRI

Fatterpekar, Girish M., Galheigo, Diogo, Narayana, Ashwatha, Johnson, Glyn and Knopp, Edmond (2012) Treatment-related change versus tumor recurrence in high-grade gliomas: a diagnostic conundrum--use of dynamic susceptibility contrast-enhanced (DSC) perfusion MRI. American Journal of Roentgenology, 198 (1). pp. 19-26. ISSN 0361-803X

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Abstract

OBJECTIVE: The purpose of this article is to address radiation necrosis, pseudoprogression, and pseudoresponse relative to high-grade gliomas and evaluate the role of conventional MRI and, in particular, dynamic susceptibility contrast-enhanced perfusion MRI in assessing such treatment-related changes from tumor recurrence. CONCLUSION: Posttreatment imaging assessment of high-grade gliomas remains challenging. Familiarity with the expected MR imaging appearances of treatment-related change and tumor recurrence will help distinguish these entities allowing appropriate management.

Item Type: Article
Uncontrolled Keywords: perfusion,pseudoprogression,pseudoresponse,radiation necrosis,tumor recurrence
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Depositing User: Pure Connector
Date Deposited: 15 Sep 2015 10:12
Last Modified: 22 Apr 2020 00:29
URI: https://ueaeprints.uea.ac.uk/id/eprint/54361
DOI: 10.2214/AJR.11.7417

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