Treatment-related change versus tumor recurrence in high-grade gliomas: a diagnostic conundrum--use of dynamic susceptibility contrast-enhanced (DSC) perfusion MRI

Fatterpekar, Girish M., Galheigo, Diogo, Narayana, Ashwatha, Johnson, Glyn and Knopp, Edmond (2012) Treatment-related change versus tumor recurrence in high-grade gliomas: a diagnostic conundrum--use of dynamic susceptibility contrast-enhanced (DSC) perfusion MRI. American Journal of Roentgenology, 198 (1). pp. 19-26. ISSN 0361-803X

Full text not available from this repository. (Request a copy)

Abstract

OBJECTIVE: The purpose of this article is to address radiation necrosis, pseudoprogression, and pseudoresponse relative to high-grade gliomas and evaluate the role of conventional MRI and, in particular, dynamic susceptibility contrast-enhanced perfusion MRI in assessing such treatment-related changes from tumor recurrence. CONCLUSION: Posttreatment imaging assessment of high-grade gliomas remains challenging. Familiarity with the expected MR imaging appearances of treatment-related change and tumor recurrence will help distinguish these entities allowing appropriate management.

Item Type:	Article
Uncontrolled Keywords:	perfusion,pseudoprogression,pseudoresponse,radiation necrosis,tumor recurrence
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Norwich Clinical Trials Unit Faculty of Medicine and Health Sciences > Research Groups > Cancer Studies
Depositing User:	Pure Connector
Date Deposited:	15 Sep 2015 10:12
Last Modified:	29 Oct 2025 20:30
URI:	https://ueaeprints.uea.ac.uk/id/eprint/54361
DOI:	10.2214/AJR.11.7417

Actions (login required)

View Item