NO metabolite flux across the human coronary circulation

Rogers, Stephen C, Khalatbari, Afshin, Datta, Borunendra N, Ellery, Sue, Paul, Vince, Frenneaux, Michael P and James, Philip E (2007) NO metabolite flux across the human coronary circulation. Cardiovascular Research, 75 (2). pp. 434-41. ISSN 0008-6363

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Abstract

The theory of a red blood cell derived nitric oxide (NO) reserve conserving NO bioactivity and delivering NO as a function of oxygen demand has been the subject of much interest. We identified the human coronary circulation as an ideal model system in which to analyse NO metabolites because of its large physiological oxygen gradient. Our objective was to identify whether oxygen drove apportion between various NO metabolite species across a single vascular bed.

Item Type:	Article
Uncontrolled Keywords:	adult,analysis of variance,coronary circulation,endothelium, vascular,erythrocytes,female,hemoglobins,humans,luminescence,male,middle aged,nitrates,nitric oxide,nitric oxide synthase,nitrites,oxygen,pulmonary artery,omega-n-methylarginine
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Cardiovascular and Metabolic Health
Depositing User:	Pure Connector
Date Deposited:	13 Mar 2015 16:48
Last Modified:	23 Apr 2023 01:02
URI:	https://ueaeprints.uea.ac.uk/id/eprint/52657
DOI:	10.1016/j.cardiores.2007.04.019

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