Red blood cell nitric oxide as an endocrine vasoregulator: A potential role in congestive heart failure

Datta, Borunendra, Tufnell-Barrett, Timothy, Bleasdale, Robert A., Jones, Christopher J. H., Beeton, Ian, Paul, Vincent, Frenneaux, Michael and James, Philip (2004) Red blood cell nitric oxide as an endocrine vasoregulator: A potential role in congestive heart failure. Circulation, 109 (11). pp. 1339-1342. ISSN 0009-7322

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Abstract

A respiratory cycle for nitric oxide (NO) would involve the formation of vasoactive metabolites between NO and hemoglobin during pulmonary oxygenation. We investigated the role of these metabolites in hypoxic tissue in vitro and in vivo in healthy subjects and patients with congestive heart failure (CHF).

Item Type:	Article
Uncontrolled Keywords:	allosteric regulation,animals,anoxia,aorta, thoracic,cardiac output,cell hypoxia,erythrocytes,female,heart failure,hemoglobins,humans,in vitro techniques,iron,lung,male,middle aged,nitric oxide,nitrogen oxides,oxygen,partial pressure,rabbits,s-nitrosoglutathione,vasodilation
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Cardiovascular and Metabolic Health
Depositing User:	Pure Connector
Date Deposited:	13 Mar 2015 16:22
Last Modified:	07 Oct 2024 15:30
URI:	https://ueaeprints.uea.ac.uk/id/eprint/52627
DOI:	10.1161/01.CIR.0000124450.07016.1D

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