Impact of chronic congestive heart failure on pharmacokinetics and vasomotor effects of infused nitrite

Maher, Abdul R, Arif, Sayqa, Madhani, Melanie, Abozguia, Khalid, Ahmed, Ibrar, Fernandez, Bernadette O, Feelisch, Martin, O'Sullivan, A G, Christopoulos, Arthur, Sverdlov, Aaron L, Ngo, Doan, Dautov, Rustem, James, Philip E, Horowitz, John D and Frenneaux, Michael P (2013) Impact of chronic congestive heart failure on pharmacokinetics and vasomotor effects of infused nitrite. British Journal of Pharmacology, 169 (3). pp. 659-70. ISSN 0007-1188

Full text not available from this repository.

Abstract

Nitrite (NO₂⁻) has recently been shown to represent a potential source of NO, in particular under hypoxic conditions. The aim of the current study was to compare the haemodynamic effects of NO₂⁻ in healthy volunteers and patients with stable congestive heart failure (CHF).

Item Type:	Article
Additional Information:	© 2013 The Authors. British Journal of Pharmacology © 2013 The British Pharmacological Society.
Uncontrolled Keywords:	aged,brachial artery,cohort studies,drug tolerance,female,forearm,heart failure,hemodynamics,humans,in vitro techniques,infusions, intra-arterial,male,metabolic clearance rate,middle aged,nitric oxide,nitroglycerin,oxidative stress,regional blood flow,saphenous vein,sodium nitrite,vasodilation,vasodilator agents,vasomotor system
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Cardiovascular and Metabolic Health
Depositing User:	Pure Connector
Date Deposited:	09 Mar 2015 07:28
Last Modified:	23 Apr 2023 00:59
URI:	https://ueaeprints.uea.ac.uk/id/eprint/52415
DOI:	10.1111/bph.12152

Actions (login required)

View Item