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ToolsDrury, Nigel E., Howell, Neil J., Calvert, Melanie J., Weber, Ralf J. M., Senanayake, Eshan L., Lewis, Michael E., Hyde, Jonathan A. J., Green, David H., Mascaro, Jorge G., Wilson, Ian C., Graham, Timothy R., Rooney, Stephen J., Viant, Mark R., Freemantle, Nick, Frenneaux, Michael P. and Pagano, Domenico and investigators (2015) The effect of perhexiline on myocardial protection during coronary artery surgery: A two-centre, randomized, double-blind, placebo-controlled trial. European Journal of Cardio-Thoracic Surgery, 47 (3). pp. 464-472. ISSN 1873-734X
Full text not available from this repository.Abstract
Perhexiline is thought to modulate metabolism by inhibiting mitochondrial carnitine palmitoyltransferase-1, reducing fatty acid uptake and increasing carbohydrate utilization. This study assessed whether preoperative perhexiline improves markers of myocardial protection in patients undergoing coronary artery bypass graft surgery and analysed its effect on the myocardial metabolome.
| Item Type: | Article |
|---|---|
| Additional Information: | © The Author 2014. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
| Faculty \ School: | Faculty of Medicine and Health Sciences > Norwich Medical School |
| UEA Research Groups: | Faculty of Medicine and Health Sciences > Research Groups > Cardiovascular and Metabolic Health |
| Depositing User: | Pure Connector |
| Date Deposited: | 25 Feb 2015 06:16 |
| Last Modified: | 23 Apr 2023 00:59 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/52410 |
| DOI: | 10.1093/ejcts/ezu238 |
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