Enhanced NO signaling in patients with Takotsubo cardiomyopathy: Short-term pain, long-term gain?

Nguyen, Thanh H, Neil, Christopher J, Sverdlov, Aaron L, Ngo, Doan T, Chan, Wai P, Heresztyn, Tamila, Chirkov, Yuliy Y, Tsikas, Dimitrios, Frenneaux, Michael P and Horowitz, John D (2013) Enhanced NO signaling in patients with Takotsubo cardiomyopathy: Short-term pain, long-term gain? Cardiovascular Drugs and Therapy, 27 (6). pp. 541-547. ISSN 0920-3206

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Abstract

Little information is available concerning the mechanism(s) underlying Takotsubo cardiomyopathy (TTC), other than evidence of associated catecholamine secretion. Given the known effects of catecholamines on endothelial function, we tested the hypothesis that TTC might also be associated with impairment of nitric oxide (NO) signaling. We now report an evaluation of NO signaling in TTC patients (vs. aged-matched controls) in relation to (a) severity of the acute attack and (b) rate of recovery.

Item Type: Article
Uncontrolled Keywords: aged,aged, 80 and over,female,humans,male,middle aged,nitric oxide,pain,signal transduction,takotsubo cardiomyopathy
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups: Faculty of Medicine and Health Sciences > Research Groups > Cardiovascular and Metabolic Health
Depositing User: Pure Connector
Date Deposited: 09 Mar 2015 07:27
Last Modified: 01 Oct 2024 15:30
URI: https://ueaeprints.uea.ac.uk/id/eprint/52303
DOI: 10.1007/s10557-013-6481-x

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