Non-invasive clinical and physical signs, symptoms and indications for identification of impending and current water-loss dehydration in older people: a diagnostic accuracy systematic review

Hooper, Lee ORCID: https://orcid.org/0000-0002-7904-3331, Abdelhamid, Asmaa, Campbell, Wayne, Chassagne, Philippe, Fletcher, Stephen, Fortes, Matt, Gaspar, Phyllis, Gilbert, Daniel, Heathcote, Adam, Kajii, Fumiko, Lindner, Gregor, Mentes, Janet, Merlani, Paolo, Needham, Rowan, Olde Rikkert, Marcel, Perren, Andreas, Powers, James, Ranson, Sheila, Rowat, Anne, Sjostrand, Fredrik, Stookey, Jodi, Stotts, Nancy, Vivanti, Angela, Waldreus, Nana, Walsh, Neil, Ward, Sean and Potter, John (2014) Non-invasive clinical and physical signs, symptoms and indications for identification of impending and current water-loss dehydration in older people: a diagnostic accuracy systematic review. In: 10th International Congress of the European Union Geriatric Medicine Society, 2014-09-17 - 2014-09-19, De dolen.

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Abstract

Introduction Water-loss dehydration is common in older people and associated with excess morbidity and mortality, but it is unclear which signs/symptoms identify dehydration in this group. Diagnostic accuracy of possible clinical and physical signs, symptoms and indications of water-loss dehydration in older people were assessed against serum osmolality or weight change (reference standards)1. Methods Structured searches were run in seven databases. Assessment of inclusion, data extraction and assessment of validity were duplicated. Where data sets included index tests and a reference standard, but were not analysed for diagnostic accuracy, reviewers analysed the data. Diagnostic accuracy of each sign, symptom or indicator was assessed against the best reference standard, and data presented in sensitivity and specificity forest plots. Pre-set minimum sensitivity was 60%, specificity 75%. Secondary analyses created receiver operating characteristic (ROC) curves for continuous tests. Results We included 24 studies (3 using published data, 21 analysing raw data sets) reporting 67 tests. No index tests were reproducibly usefully diagnostic of water-loss dehydration in older people, but promising signs/symptoms, which need further assessment, are shown in the table. There was sufficient evidence to suggest that some signs/symptoms should not be used to indicate dehydration (table). Conclusions No single sign/symptom was diagnostic of water-loss dehydration in older people. Individual signs should not be used in this population to indicate dehydration as they will miss many with dehydration, and wrongly label those adequately hydrated. Promising signs identified by this review need to be further assessed. 1. Hooper L et al, Cochrane Library (protocol) 2011: CD009647-DOI:1002/14651858.

Item Type:	Conference or Workshop Item (Poster)
Uncontrolled Keywords:	dehydration,older adults,systematic review,diagnostic accuracy
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Epidemiology and Public Health Faculty of Medicine and Health Sciences > Research Groups > Public Health and Health Services Research (former - to 2023) Faculty of Medicine and Health Sciences > Research Groups > Cardiovascular and Metabolic Health Faculty of Medicine and Health Sciences > Research Groups > Nutrition and Preventive Medicine Faculty of Medicine and Health Sciences > Research Groups > Health Services and Primary Care Faculty of Medicine and Health Sciences > Research Centres > Population Health
Depositing User:	Pure Connector
Date Deposited:	23 Sep 2014 14:08
Last Modified:	19 Oct 2023 03:58
URI:	https://ueaeprints.uea.ac.uk/id/eprint/50232
DOI:	10.1016/S1878-7649(14)70148-2

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