Smokers with active Crohn's disease have a clinically relevant dysbiosis of the gastrointestinal microbiota

Benjamin, Jane L, Hedin, Charlotte R H, Koutsoumpas, Andreas, Ng, Siew C, McCarthy, Neil E, Prescott, Natalie J, Pessoa-Lopes, Pedro, Mathew, Christopher G, Sanderson, Jeremy, Hart, Ailsa L, Kamm, Michael A, Knight, Stella C, Forbes, Alastair ORCID: https://orcid.org/0000-0001-7416-9843, Stagg, Andrew J, Lindsay, James O and Whelan, Kevin (2012) Smokers with active Crohn's disease have a clinically relevant dysbiosis of the gastrointestinal microbiota. Inflammatory Bowel Diseases, 18 (6). pp. 1092-100. ISSN 1078-0998

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Abstract

Patients with Crohn's disease (CD) have an intestinal dysbiosis with components of the microbiota exerting differential immune effects. Smoking is associated with an increased incidence of CD, more frequent relapse, and greater burden of surgery. This study aimed to investigate the association between smoking and the intestinal microbiota in patients with active CD.

Item Type:	Article
Additional Information:	Copyright © 2011 Crohn's & Colitis Foundation of America, Inc.
Uncontrolled Keywords:	adult,case-control studies,colony count, microbial,crohn disease,dna, bacterial,feces,female,gastrointestinal tract,humans,in situ hybridization, fluorescence,male,metagenome,prospective studies,smoking
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Gastroenterology and Gut Biology Faculty of Medicine and Health Sciences > Research Groups > Nutrition and Preventive Medicine
Depositing User:	Pure Connector
Date Deposited:	06 Aug 2014 10:39
Last Modified:	21 Oct 2022 00:03
URI:	https://ueaeprints.uea.ac.uk/id/eprint/49834
DOI:	10.1002/ibd.21864

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