Pradeep, Archana, Proudlock, Frank A., Awan, Musarat, Bush, Glen, Collier, Jacqueline and Gottlob, Irene (2014) An educational intervention to improve adherence to high-dosage patching regimen for amblyopia: A randomised controlled trial. British Journal of Ophthalmology, 98 (7). pp. 865-870. ISSN 0007-1161
Full text not available from this repository. (Request a copy)Abstract
Background: Previous reports suggest that adherence to patching is a major issue in amblyopia treatment. We tested with an unmasked randomised controlled clinical trial whether an intense educational/motivational intervention improves adherence when a high-dose regime is prescribed. Methods: 62 children with newly diagnosed amblyopia were randomly allocated into two treatment arms with and without educational/motivational intervention material. Both were prescribed patching 10 h/day, 6 days/week for a fixed period of 12 weeks. The intervention arm received an educational/motivational intervention before patching which included information booklets, video, a cartoon story book, sticker charts and a dedicated session with a researcher. The control arm received the usual clinical information. The primary outcome measure was adherence measured using electronic occlusion dose monitors where a success/failure binary outcome was used to account for participants who dropped out of the study defined as patching >4 h/day. Visual outcome, expressed as percentage visual deficit, was measured as secondary outcome. Results: The intervention increased adherence success rate from 45.2% in the control group to 80.6% in the intervention group (p=0.0027). However, visual outcome was not significantly better in the intervention group (p=0.190). Conclusions: Our study shows that an intense educational/motivational intervention can improve adherence to patching to high prescribed doses although no significant improvement in visual outcome was observed. Trials registration number: ISRCTN05346737 (International Standard Randomised Controlled Trial Number Register).
Item Type: | Article |
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Faculty \ School: | Faculty of Social Sciences > School of Psychology Faculty of Social Sciences |
UEA Research Groups: | Faculty of Medicine and Health Sciences > Research Groups > Participation (former - to 2013) Faculty of Social Sciences > Research Groups > Developmental Science Faculty of Social Sciences > Research Groups > Cognition, Action and Perception Faculty of Social Sciences > Research Groups > Social Cognition Research Group |
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Depositing User: | Pure Connector |
Date Deposited: | 25 Jul 2014 13:48 |
Last Modified: | 21 Oct 2022 00:01 |
URI: | https://ueaeprints.uea.ac.uk/id/eprint/49716 |
DOI: | 10.1136/bjophthalmol-2013-304187 |
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