Diverse effects of the CARD15 and IBD5 loci on clinical phenotype in 630 patients with Crohn's disease

Onnie, Clive M, Fisher, Sheila A, Prescott, Natalie J, Mirza, Muddassar M, Green, Peter, Sanderson, Jeremy, Forbes, Alastair ORCID: https://orcid.org/0000-0001-7416-9843, Lewis, Cathryn M and Mathew, Christopher G (2008) Diverse effects of the CARD15 and IBD5 loci on clinical phenotype in 630 patients with Crohn's disease. European Journal of Gastroenterology & Hepatology, 20 (1). pp. 37-45. ISSN 0954-691X

Full text not available from this repository. (Request a copy)

Abstract

Genetic variants at the CARD15 and IBD5 loci are strongly associated with Crohn's disease (CD), but evidence of the effect of these variants on the clinical expression of CD is conflicting and has often been hampered by small sample sizes. We studied 630 well-characterized patients to clarify the genotype/phenotype relationship in CD.

Item Type:	Article
Uncontrolled Keywords:	adolescent,adult,age of onset,child,crohn disease,female,gene frequency,genotype,granuloma,humans,ileitis,linkage disequilibrium,male,mutation,nod2 signaling adaptor protein,phenotype,postoperative complications,recurrence
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Gastroenterology and Gut Biology Faculty of Medicine and Health Sciences > Research Groups > Nutrition and Preventive Medicine
Depositing User:	Pure Connector
Date Deposited:	06 Aug 2014 10:52
Last Modified:	21 Oct 2022 00:01
URI:	https://ueaeprints.uea.ac.uk/id/eprint/49696
DOI:	10.1097/MEG.0b013e3282f1622b

Actions (login required)

View Item