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Forbes, Alastair 
ORCID: https://orcid.org/0000-0001-7416-9843 and Kalantzis, Tommy
(2006)
Crohn's disease:the cold chain hypothesis.
International Journal of Colorectal Disease, 21 (5).
pp. 399-401.
ISSN 0179-1958
Abstract
A recent published hypothesis proposed that Crohn's disease was provoked by infantile exposure to micro-organisms that can survive refrigerator temperature. A case-control study was accordingly devised. The mean age at first fridge was 5.6 years amongst 88 patients with Crohn's disease, 5.5 years in 88 patients with ulcerative colitis (UC) and 7.6 years in 88 controls, but a majority of individuals had always been exposed to refrigerated food. Differences were more striking in subjects aged above the median (10.3, 10.9 and 15.0 years for Crohn's disease, UC and controls, respectively). This support for the hypothesis reached statistical significance for those with Crohn's disease compared to the controls (p=0.045).
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | adolescent,adult,bacteria,case-control studies,child,child, preschool,crohn disease,female,food microbiology,humans,male,refrigeration |
| Faculty \ School: | Faculty of Medicine and Health Sciences > Norwich Medical School |
| UEA Research Groups: | Faculty of Medicine and Health Sciences > Research Groups > Gastroenterology and Gut Biology Faculty of Medicine and Health Sciences > Research Groups > Nutrition and Preventive Medicine |
| Depositing User: | Pure Connector |
| Date Deposited: | 06 Aug 2014 10:44 |
| Last Modified: | 20 Oct 2022 23:59 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/49648 |
| DOI: | 10.1007/s00384-005-0003-7 |
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