Associations of allelic variants of the multidrug resistance gene (ABCB1 or MDR1) and inflammatory bowel disease and their effects on disease behavior:a case-control and meta-analysis study

Onnie, Clive M, Fisher, Sheila A, Pattni, Reenal, Sanderson, Jeremy, Forbes, Alastair ORCID: https://orcid.org/0000-0001-7416-9843, Lewis, Cathryn M and Mathew, Christopher G (2006) Associations of allelic variants of the multidrug resistance gene (ABCB1 or MDR1) and inflammatory bowel disease and their effects on disease behavior:a case-control and meta-analysis study. Inflammatory Bowel Diseases, 12 (4). pp. 263-71. ISSN 1078-0998

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Abstract

Allelic variants of the ATP-binding cassette, subfamily B member 1 (ABCB1), also known as the multidrug resistance gene (MDR1) that encodes the membrane-bound efflux transporter P-glycoprotein 170 (PGP-170), have been associated with inflammatory bowel disease but with conflicting results.

Item Type:	Article
Uncontrolled Keywords:	adolescent,adult,aged,aged, 80 and over,alleles,child,child, preschool,dna,disease progression,female,follow-up studies,gene frequency,genotype,humans,inflammatory bowel diseases,male,middle aged,organic anion transporters,p-glycoprotein,polymorphism, genetic,retrospective studies
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Gastroenterology and Gut Biology Faculty of Medicine and Health Sciences > Research Groups > Nutrition and Preventive Medicine
Depositing User:	Pure Connector
Date Deposited:	06 Aug 2014 10:52
Last Modified:	20 Oct 2022 23:59
URI:	https://ueaeprints.uea.ac.uk/id/eprint/49647
DOI:	10.1097/01.MIB.0000209791.98866.ba

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