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Kitchen, P A, Fitzgerald, A J, Goodlad, R A, Barley, N F, Ghatei, M A, Legon, S, Bloom, S R, Price, A, Walters, J R and Forbes, A 
ORCID: https://orcid.org/0000-0001-7416-9843
(2000)
Glucagon-like peptide-2 increases sucrase-isomaltase but not caudal-related homeobox protein-2 gene expression.
AJP: Gastrointestinal and Liver Physiology, 278 (3).
G425-8.
ISSN 0193-1857
Abstract
To determine the effect of glucagon-like peptide-2 (GLP-2) on sucrase-isomaltase and caudal-related homeobox protein-2 (Cdx-2) gene expression, male Wistar rats were divided into total parenteral nutrition (TPN)-fed and GLP-2-treated, TPN-fed groups. TPN was given via a jugular line, inserted under anesthesia, for 7 days. The treatment group received 40 microg/day of GLP-2 intravenously with the TPN diet. The small intestine and colon were weighed and measured. Tissue was obtained from the jejunum, terminal ileum, and midcolon. RNA analysis, morphometry, and microdissection were performed. The weight of the small intestine of GLP-2-treated rats was greater than that of TPN-fed rats (P
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | animals,colon,gene expression,glucagon-like peptide 2,glucagon-like peptides,homeodomain proteins,ileum,jejunum,male,parenteral nutrition, total,peptides,rats,rats, wistar,sucrase-isomaltase complex,trans-activators |
| Faculty \ School: | Faculty of Medicine and Health Sciences > Norwich Medical School |
| UEA Research Groups: | Faculty of Medicine and Health Sciences > Research Groups > Gastroenterology and Gut Biology Faculty of Medicine and Health Sciences > Research Groups > Nutrition and Preventive Medicine |
| Depositing User: | Pure Connector |
| Date Deposited: | 06 Aug 2014 10:48 |
| Last Modified: | 20 Oct 2022 23:58 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/49568 |
| DOI: | 10.1152/ajpgi.2000.278.3.G425# |
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