Metastatic islet cell tumour with clinical manifestations of insulin and glucagon excess:successful treatment by hepatic artery embolization and chemotherapy

Lee, S M, Forbes, A ORCID: https://orcid.org/0000-0001-7416-9843 and Williams, R (1988) Metastatic islet cell tumour with clinical manifestations of insulin and glucagon excess:successful treatment by hepatic artery embolization and chemotherapy. European Journal of Surgical Oncology, 14 (3). pp. 265-268. ISSN 0748-7983

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Abstract

A patient with a metastatic islet cell tumour with clinical features of both insulin and glucagon excess is reported. This appears to be only the third such case in the literature and the first in whom the initial symptoms were of the glucagonoma syndrome. Radiologically and biochemically defined complete remission was induced within 9 months of hepatic arterial embolization and cyclical chemotherapy with 5-fluorouracil and streptozocin; complete remission has been maintained for a further 23 months without therapy.

Item Type:	Article
Uncontrolled Keywords:	adenoma, islet cell,combined modality therapy,embolization, therapeutic,female,fluorouracil,glucagon,glucagonoma,hepatic artery,humans,insulin,middle aged,neoplasm metastasis,pancreatic neoplasms,streptozocin
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Gastroenterology and Gut Biology Faculty of Medicine and Health Sciences > Research Groups > Nutrition and Preventive Medicine
Depositing User:	Pure Connector
Date Deposited:	06 Aug 2014 10:50
Last Modified:	24 Oct 2022 23:59
URI:	https://ueaeprints.uea.ac.uk/id/eprint/49510
DOI:

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