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Powers, H J, Wright, A J and Fairweather-Tait, S J 
ORCID: https://orcid.org/0000-0002-1413-5569
(1988)
The effect of riboflavin deficiency in rats on the absorption and distribution of iron.
British Journal of Nutrition, 59 (3).
pp. 381-387.
ISSN 0007-1145
Abstract
1. Riboflavin may play a part in the transport of iron across the gastrointestinal mucosa. Fe absorption was measured in the rat by monitoring whole-body retention of a dose of 59Fe using a small-animal gamma-counter. 2. Female Norwegian Hooded rats were fed on a diet deficient in riboflavin (B2-) from 5 weeks of age. Control animals, fed on a complete diet (B2+), were weight-matched to rats fed on the B2- diet. After 7 weeks all rats were fed on a test meal extrinsically labelled with 59Fe and whole-body radioactivity measured for 15 d. 3. Riboflavin deficiency was associated with a reduction in the percentage of the dose absorbed and an increase in the rate of loss of Fe post absorption. 4. A smaller percentage of the absorbed dose was present in the livers of the riboflavin-deficient animals.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | animals,biological transport,female,intestinal absorption,intestinal mucosa,iron,organ size,rats,riboflavin deficiency,tissue distribution |
| Faculty \ School: | Faculty of Medicine and Health Sciences > Norwich Medical School Faculty of Social Sciences > Norwich Business School |
| UEA Research Groups: | Faculty of Medicine and Health Sciences > Research Groups > Nutrition and Preventive Medicine Faculty of Medicine and Health Sciences > Research Groups > Musculoskeletal Medicine Faculty of Medicine and Health Sciences > Research Centres > Lifespan Health |
| Depositing User: | Pure Connector |
| Date Deposited: | 05 Aug 2014 12:56 |
| Last Modified: | 19 Oct 2023 01:20 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/49253 |
| DOI: |
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