Comparison of fast atom bombardment mass spectrometry and thermal ionization quadrupole mass spectrometry for the measurement of zinc absorption in human nutrition studies

Eagles, John, Fairweather-Tait, Susan J. ORCID: https://orcid.org/0000-0002-1413-5569, Portwood, David E., Self, Ron, Götz, Adolf and Heumann, Klaus G. (1989) Comparison of fast atom bombardment mass spectrometry and thermal ionization quadrupole mass spectrometry for the measurement of zinc absorption in human nutrition studies. Analytical Chemistry, 61 (9). pp. 1023-1025. ISSN 0003-2700

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Abstract

A method is described for the measurement of apparent zinc absorption in human nutrition studies. An enriched source of the stable isotope 67Zn was given to adult subjects together with a wheat cereal and the unabsorbed 67Zn measured in the feces. After drying, subsamples of the homogenized fecal material were ashed at 480 degrees C, purified for analysis by ion exchange chromatography, and the 64Zn/67Zn ratios determined by both fast atom bombardment mass spectrometry and thermal ionization quadrupole mass spectrometry. Good agreement was found between the two sets of results with mean precisions of approximately 0.5% for both techniques.

Item Type:	Article
Uncontrolled Keywords:	biological availability,humans,mass spectrometry,nutritional physiological phenomena,zinc
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Nutrition and Preventive Medicine Faculty of Medicine and Health Sciences > Research Groups > Musculoskeletal Medicine Faculty of Medicine and Health Sciences > Research Centres > Lifespan Health
Depositing User:	Pure Connector
Date Deposited:	05 Aug 2014 12:54
Last Modified:	19 Oct 2023 01:20
URI:	https://ueaeprints.uea.ac.uk/id/eprint/49246
DOI:	10.1021/ac00184a021

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