Fairweather-Tait, Susan ORCID: https://orcid.org/0000-0002-1413-5569, Phillips, Ian, Wortley, Gary, Harvey, Linda and Glahn, Ray (2007) The use of solubility, dialyzability, and Caco-2 cell methods to predict iron bioavailability. International Journal for Vitamin and Nutrition Research, 77 (3). pp. 158-165. ISSN 0300-9831
Full text not available from this repository. (Request a copy)Abstract
An update on in vitro methods employed to assess iron bioavailability is presented. Solubility and dialyzability are not useful predictors of iron absorption, whereas Caco-2 cell models provide useful comparisons on the availability of iron from different sources. Strengths and weaknesses of in vitro approaches are briefly described, including the need to characterize Caco-2 cells in order to interpret results correctly. Further developments are required to refine Caco-2 model systems, including optimization and standardization of methods.
Item Type: | Article |
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Uncontrolled Keywords: | biological availability,caco-2 cells,dialysis,humans,intestinal absorption,iron, dietary,models, biological,predictive value of tests,solubility |
Faculty \ School: | Faculty of Medicine and Health Sciences > Norwich Medical School |
UEA Research Groups: | Faculty of Medicine and Health Sciences > Research Groups > Nutrition and Preventive Medicine Faculty of Medicine and Health Sciences > Research Groups > Musculoskeletal Medicine Faculty of Medicine and Health Sciences > Research Centres > Lifespan Health |
Depositing User: | Pure Connector |
Date Deposited: | 29 Jul 2014 12:22 |
Last Modified: | 19 Oct 2023 01:18 |
URI: | https://ueaeprints.uea.ac.uk/id/eprint/49131 |
DOI: | 10.1024/0300-9831.77.3.158 |
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