Confocal laser endomicroscopy is a new imaging modality for recognition of intramucosal bacteria in inflammatory bowel disease in vivo

Moussata, Driffa, Goetz, Martin, Gloeckner, Annabel, Kerner, Marcus, Campbell, Barry, Hoffman, Arthur, Biesterfeld, Stephan, Flourie, Bernard, Saurin, Jean-Christophe, Galle, Peter R, Neurath, Markus F, Watson, Alastair J M ORCID: https://orcid.org/0000-0003-3326-0426 and Kiesslich, Ralf (2011) Confocal laser endomicroscopy is a new imaging modality for recognition of intramucosal bacteria in inflammatory bowel disease in vivo. Gut, 60 (1). pp. 26-33. ISSN 0017-5749

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Abstract

Interaction of bacteria with the immune system within the intestinal mucosa plays a key role in the pathogenesis of inflammatory bowel disease (IBD). The aim of the current study was to develop a fluorescein-aided confocal laser endomicroscopy (CLE) method to visualise intramucosal enteric bacteria in vivo and to determine the involved mucosal area in the colon and ileum in patients with ulcerative colitis (UC) and Crohn's disease (CD).

Item Type:	Article
Uncontrolled Keywords:	animals,colitis, ulcerative,colon,colonoscopy,crohn disease,enterobacteriaceae,escherichia coli,humans,ileum,in situ hybridization, fluorescence,inflammatory bowel diseases,intestinal mucosa,male,mice,mice, inbred c57bl,microscopy, confocal,prospective studies,retrospective studies
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Gastroenterology and Gut Biology
Depositing User:	Pure Connector
Date Deposited:	07 Jul 2014 13:44
Last Modified:	21 Aug 2023 00:25
URI:	https://ueaeprints.uea.ac.uk/id/eprint/48952
DOI:	10.1136/gut.2010.213264

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