Gene expression of transporters and phase I/II metabolic enzymes in murine small intestine during fasting

van den Bosch, Heleen M, Bünger, Meike, de Groot, Philip J, van der Meijde, Jolanda, Hooiveld, Guido J E J and Müller, Michael (2007) Gene expression of transporters and phase I/II metabolic enzymes in murine small intestine during fasting. BMC Genomics, 8. ISSN 1471-2164

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Abstract

Fasting has dramatic effects on small intestinal transport function. However, little is known on expression of intestinal transport and phase I/II metabolism genes during fasting and the role the fatty acid-activated transcription factor PPARalpha may play herein. We therefore investigated the effects of fasting on expression of these genes using Affymetrix GeneChip MOE430A arrays and quantitative RT-PCR.

Item Type: Article
Additional Information: © 2007 van den Bosch et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Uncontrolled Keywords: atp-binding cassette transporters,animals,fasting,gene expression profiling,gene expression regulation,small intestine,metabolic networks and pathways,mice,oligonucleotide array sequence analysis,organic anion transporters,ppar alpha,time factors
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Depositing User: Pure Connector
Date Deposited: 07 Jul 2014 12:02
Last Modified: 14 Sep 2020 07:04
URI: https://ueaeprints.uea.ac.uk/id/eprint/47726
DOI: 10.1186/1471-2164-8-267

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