Gene expression of transporters and phase I/II metabolic enzymes in murine small intestine during fasting

van den Bosch, Heleen M, Bünger, Meike, de Groot, Philip J, van der Meijde, Jolanda, Hooiveld, Guido J E J and Müller, Michael ORCID: https://orcid.org/0000-0002-5930-9905 (2007) Gene expression of transporters and phase I/II metabolic enzymes in murine small intestine during fasting. BMC Genomics, 8. ISSN 1471-2164

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Abstract

Fasting has dramatic effects on small intestinal transport function. However, little is known on expression of intestinal transport and phase I/II metabolism genes during fasting and the role the fatty acid-activated transcription factor PPARalpha may play herein. We therefore investigated the effects of fasting on expression of these genes using Affymetrix GeneChip MOE430A arrays and quantitative RT-PCR.

Item Type:	Article
Additional Information:	© 2007 van den Bosch et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Uncontrolled Keywords:	atp-binding cassette transporters,animals,fasting,gene expression profiling,gene expression regulation,small intestine,metabolic networks and pathways,mice,oligonucleotide array sequence analysis,organic anion transporters,ppar alpha,time factors
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Nutrition and Preventive Medicine Faculty of Medicine and Health Sciences > Research Groups > Gastroenterology and Gut Biology Faculty of Medicine and Health Sciences > Research Centres > Metabolic Health
Depositing User:	Pure Connector
Date Deposited:	07 Jul 2014 12:02
Last Modified:	06 Jun 2024 14:47
URI:	https://ueaeprints.uea.ac.uk/id/eprint/47726
DOI:	10.1186/1471-2164-8-267

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