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Lichtenstein, Laeticia, Berbée, Jimmy F P, van Dijk, Susan J, van Dijk, Ko Willems, Bensadoun, André, Kema, Ido P, Voshol, Peter J, Müller, Michael 
ORCID: https://orcid.org/0000-0002-5930-9905, Rensen, Patrick C N and Kersten, Sander
(2007)
Angptl4 upregulates cholesterol synthesis in liver via inhibition of LPL- and HL-dependent hepatic cholesterol uptake.
Arteriosclerosis, Thrombosis, and Vascular Biology, 27 (11).
pp. 2420-2427.
ISSN 1079-5642
Abstract
Dysregulation of plasma lipoprotein levels may increase the risk for atherosclerosis. Recently, angiopoietin-like protein 4, also known as fasting-induced adipose factor Fiaf, was uncovered as a novel modulator of plasma lipoprotein metabolism. Here we take advantage of the fasting-dependent phenotype of Angptl4-transgenic (Angptl4-Tg) mice to better characterize the metabolic function of Angptl4.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | angiopoietins,animals,biosynthetic pathways,blood glucose,blood proteins,cholesterol,fasting,fatty acids,insulin resistance,lipolysis,lipoprotein lipase,liver,mice,mice, transgenic,triglycerides |
| Faculty \ School: | Faculty of Medicine and Health Sciences > Norwich Medical School |
| UEA Research Groups: | Faculty of Medicine and Health Sciences > Research Groups > Nutrition and Preventive Medicine Faculty of Medicine and Health Sciences > Research Groups > Gastroenterology and Gut Biology Faculty of Medicine and Health Sciences > Research Centres > Metabolic Health |
| Depositing User: | Pure Connector |
| Date Deposited: | 21 Feb 2014 11:50 |
| Last Modified: | 06 Jun 2024 14:47 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/47725 |
| DOI: | 10.1161/ATVBAHA.107.151894 |
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