Exploring genetic determinants of plasma total cholesterol levels and their predictive value in a longitudinal study

Lu, Yingchang, Feskens, Edith J M, Boer, Jolanda M A, Imholz, Sandra, Verschuren, W M Monique, Wijmenga, Cisca, Vaarhorst, Anika, Slagboom, Eline, Müller, Michael ORCID: https://orcid.org/0000-0002-5930-9905 and Dollé, Martijn E T (2010) Exploring genetic determinants of plasma total cholesterol levels and their predictive value in a longitudinal study. Atherosclerosis, 213 (1). pp. 200-205.

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Abstract

Plasma total cholesterol (TC) levels are highly genetically determined. Although ample evidence of genetic determination of separate lipoprotein cholesterol levels has been reported, using TC level directly as a phenotype in a relatively large broad-gene based association study has not been reported to date.

Item Type:	Article
Additional Information:	Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.
Uncontrolled Keywords:	adult,body mass index,cholesterol,female,genetic predisposition to disease,genome-wide association study,humans,lipoproteins,longitudinal studies,male,middle aged,phenotype,polymorphism, single nucleotide,predictive value of tests,risk
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Nutrition and Preventive Medicine Faculty of Medicine and Health Sciences > Research Groups > Gastroenterology and Gut Biology Faculty of Medicine and Health Sciences > Research Centres > Metabolic Health
Depositing User:	Pure Connector
Date Deposited:	10 Jun 2014 20:48
Last Modified:	06 Jun 2024 14:46
URI:	https://ueaeprints.uea.ac.uk/id/eprint/47672
DOI:	10.1016/j.atherosclerosis.2010.08.053

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