Progression of lumbar disc degeneration over a decade:a heritability study

Williams, Frances M K, Popham, Maria, Sambrook, Philip N, Jones, Annette F, Spector, Tim D, MacGregor, Alex J and Macgregor, Alexander ORCID: https://orcid.org/0000-0003-2163-2325 (2011) Progression of lumbar disc degeneration over a decade:a heritability study. Annals of the Rheumatic Diseases, 70 (7). pp. 1203-7. ISSN 0003-4967

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Abstract

Lumbar disc degeneration (LDD) is prevalent, age-related and contributes to low back pain. Cross-sectional LDD as determined by MRI scan is known to be highly heritable. The authors postulated that the rate of progression might also be controlled by genetic factors.

Item Type:	Article
Uncontrolled Keywords:	adult,aged,disease progression,diseases in twins,female,follow-up studies,genetic predisposition to disease,humans,intervertebral disc degeneration,lumbar vertebrae,magnetic resonance imaging,male,middle aged,phenotype,twins, dizygotic,twins, monozygotic
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Epidemiology and Public Health Faculty of Medicine and Health Sciences > Research Groups > Musculoskeletal Medicine Faculty of Medicine and Health Sciences > Research Groups > Nutrition and Preventive Medicine Faculty of Medicine and Health Sciences > Research Groups > Public Health and Health Services Research (former - to 2023) Faculty of Science > Research Groups > Norwich Epidemiology Centre Faculty of Medicine and Health Sciences > Research Groups > Norwich Epidemiology Centre
Depositing User:	Pure Connector
Date Deposited:	27 Jan 2014 13:56
Last Modified:	19 Apr 2023 00:01
URI:	https://ueaeprints.uea.ac.uk/id/eprint/47225
DOI:	10.1136/ard.2010.146001

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