The third hydrogenase: A ferracyclic carbamoyl with close structural analogy to the active site of Hmd

Turrell, Peter J., Wright, Joseph A. ORCID: https://orcid.org/0000-0001-9603-1001, Peck, Jamie N. T., Oganesyan, Vasily S. ORCID: https://orcid.org/0000-0002-8738-1146 and Pickett, Christopher J. (2010) The third hydrogenase: A ferracyclic carbamoyl with close structural analogy to the active site of Hmd. Angewandte Chemie International Edition, 49 (41). pp. 7508-7511. ISSN 1433-7851

Full text not available from this repository. (Request a copy)

Abstract

The synthesis of a close structural analogue of the active site of [Fe]-hydrogenase is described (see structure; C gray, H dark blue, Fe green, N light blue, O red, S yellow). Nature most probably constructs the five membered ferracyclic ring to poise the 2-hydroxy pyridine substituent in a position to assist the heterolytic cleavage of dihydrogen, and the accessibility of the analogue should now provide opportunities for probing this.

Item Type: Article
Faculty \ School: Faculty of Science > School of Chemistry
Depositing User: Pure Connector
Date Deposited: 18 Dec 2013 12:40
Last Modified: 09 Feb 2023 13:38
URI: https://ueaeprints.uea.ac.uk/id/eprint/47070
DOI: 10.1002/anie.v49:41

Actions (login required)

View Item View Item