A gene expression-based predictor for myeloma patients at high risk of developing bone disease on bisphosphonate treatment

Wu, Ping, Walker, Brian A, Brewer, Daniel ORCID: https://orcid.org/0000-0003-4753-9794, Gregory, Walter M, Ashcroft, John, Ross, Fiona M, Jackson, Graham H, Child, Anthony J, Davies, Faith E and Morgan, Gareth J (2011) A gene expression-based predictor for myeloma patients at high risk of developing bone disease on bisphosphonate treatment. Clinical Cancer Research, 17 (19). pp. 6347-55. ISSN 1078-0432

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Abstract

Myeloma bone disease impairs quality of life and is associated with impaired survival. Even with effective bisphosphonate treatment, a significant proportion of patients still develop skeletal-related events (SRE). Identifying such patients at presentation would allow treatment modification.

Item Type:	Article
Additional Information:	©2011 AACR
Uncontrolled Keywords:	aged,bone diseases,diphosphonates,gene expression profiling,humans,models, theoretical,multiple myeloma,predictive value of tests,risk,validation studies as topic
Faculty \ School:	Faculty of Science > School of Biological Sciences
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Cancer Studies Faculty of Medicine and Health Sciences > Research Centres > Metabolic Health
Depositing User:	Pure Connector
Date Deposited:	06 Jan 2014 14:08
Last Modified:	19 Oct 2023 01:15
URI:	https://ueaeprints.uea.ac.uk/id/eprint/47028
DOI:	10.1158/1078-0432.CCR-11-0994

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