A gene expression-based predictor for myeloma patients at high risk of developing bone disease on bisphosphonate treatment

Wu, Ping, Walker, Brian A, Brewer, Daniel, Gregory, Walter M, Ashcroft, John, Ross, Fiona M, Jackson, Graham H, Child, Anthony J, Davies, Faith E and Morgan, Gareth J (2011) A gene expression-based predictor for myeloma patients at high risk of developing bone disease on bisphosphonate treatment. Clinical Cancer Research, 17 (19). pp. 6347-55. ISSN 1078-0432

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Abstract

Myeloma bone disease impairs quality of life and is associated with impaired survival. Even with effective bisphosphonate treatment, a significant proportion of patients still develop skeletal-related events (SRE). Identifying such patients at presentation would allow treatment modification.

Item Type:	Article
Additional Information:	©2011 AACR
Uncontrolled Keywords:	aged,bone diseases,diphosphonates,gene expression profiling,humans,models, theoretical,multiple myeloma,predictive value of tests,risk,validation studies as topic
Faculty \ School:	Faculty of Science > School of Biological Sciences
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Cancer Studies Faculty of Medicine and Health Sciences > Research Centres > Metabolic Health
Depositing User:	Pure Connector
Date Deposited:	06 Jan 2014 14:08
Last Modified:	06 Feb 2025 04:48
URI:	https://ueaeprints.uea.ac.uk/id/eprint/47028
DOI:	10.1158/1078-0432.CCR-11-0994

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