Trypanocidal activity of salinomycin is due to sodium influx followed by cell swelling

Steverding, Dietmar and Sexton, Darren W. (2013) Trypanocidal activity of salinomycin is due to sodium influx followed by cell swelling. Parasites & Vectors, 6. ISSN 1756-3305

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Abstract

The few currently available drugs for treatment of African trypanosomiasis are outdated and show problems with toxicity and resistance. Hence, there is an urgent need for the discovery and development of new anti-trypanosomal agents.

Item Type:	Article
Uncontrolled Keywords:	antiprotozoal agents,inhibitory concentration 50,osmotic pressure,pyrans,sodium,trypanosoma brucei brucei
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Gastroenterology and Gut Biology
Depositing User:	Pure Connector
Date Deposited:	24 Jan 2014 12:42
Last Modified:	24 Oct 2022 05:48
URI:	https://ueaeprints.uea.ac.uk/id/eprint/46771
DOI:	10.1186/1756-3305-6-78

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