Scott, Jonathan P R, Sale, Craig, Greeves, Julie P, Casey, Anna, Dutton, John and Fraser, William D (2012) Effect of fasting versus feeding on the bone metabolic response to running. Bone, 51 (6). pp. 990-9. ISSN 8756-3282
Full text not available from this repository.Abstract
Individuals often perform exercise in the fasted state, but the effects on bone metabolism are not currently known. We compared the effect of an overnight fast with feeding a mixed meal on the bone metabolic response to treadmill running. Ten, physically-active males aged 28 ± 4y (mean ±SD) completed two, counterbalanced, 8d trials. After 3d on a standardised diet, participants performed 60 min of treadmill running at 65% VO(2max) on Day 4 following an overnight fast (FAST) or a standardised breakfast (FED). Blood samples were collected at baseline, before and during exercise, for 3h after exercise, and on four consecutive follow-up days (FU1-FU4). Plasma/serum were analysed for the c-terminal telopeptide region of collagen type 1 (β-CTX), n-terminal propeptides of procollagen type 1 (P1NP), osteocalcin (OC), bone alkaline phosphatase (bone ALP), parathyroid hormone (PTH), albumin-adjusted calcium, phosphate, osteoprotegerin (OPG), cortisol, leptin and ghrelin. Only the β-CTX response was significantly affected by feeding. Pre-exercise concentrations decreased more in FED compared with FAST (47% vs 26%, P
Item Type: | Article |
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Additional Information: | Copyright © 2012 Elsevier Inc. All rights reserved. |
Uncontrolled Keywords: | adult,bone resorption,bone and bones,fasting,ghrelin,humans,leptin,male,osteocalcin,parathyroid hormone,procollagen,running |
Faculty \ School: | Faculty of Medicine and Health Sciences > Norwich Medical School |
UEA Research Groups: | Faculty of Medicine and Health Sciences > Research Groups > Musculoskeletal Medicine Faculty of Medicine and Health Sciences > Research Centres > Metabolic Health |
Depositing User: | Pure Connector |
Date Deposited: | 20 Jan 2014 16:22 |
Last Modified: | 14 Oct 2025 23:42 |
URI: | https://ueaeprints.uea.ac.uk/id/eprint/46374 |
DOI: | 10.1016/j.bone.2012.08.128 |
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