Antithrombotic therapy with fondaparinux in relation to interventional management strategy in patients with ST- and non-ST-segment elevation acute coronary syndromes:an individual patient-level combined analysis of the Fifth and Sixth Organization to Assess Strategies in Ischemic Syndromes (OASIS 5 and 6) randomized trials

Mehta, Shamir R, Boden, William E, Eikelboom, John W, Flather, Marcus, Steg, P Gabriel, Avezum, Alvaro, Afzal, Rizwan, Piegas, Leopoldo S, Faxon, David P, Widimsky, Petr, Budaj, Andrzej, Chrolavicius, Susan, Rupprecht, Hans-Jurgen, Jolly, Sanjit, Granger, Christopher B, Fox, Keith A A, Bassand, Jean-Pierre and Yusuf, Salim and OASIS 5 and 6 Investigators (2008) Antithrombotic therapy with fondaparinux in relation to interventional management strategy in patients with ST- and non-ST-segment elevation acute coronary syndromes:an individual patient-level combined analysis of the Fifth and Sixth Organization to Assess Strategies in Ischemic Syndromes (OASIS 5 and 6) randomized trials. Circulation, 118 (20). pp. 2038-46. ISSN 0009-7322

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Abstract

The Fifth and Sixth Organization to Assess Strategies in Ischemic Syndromes (OASIS 5 and 6) trials evaluated fondaparinux, a synthetic factor Xa inhibitor, in patients with non-ST- and ST-segment elevation acute coronary syndromes, respectively. Combined results for these 2 trials on major efficacy and safety outcomes and data on the effects of fondaparinux in relation to interventional management strategy have not been previously reported.

Item Type:	Article
Uncontrolled Keywords:	acute coronary syndrome,aged,angioplasty, balloon, coronary,anticoagulants,double-blind method,drug administration schedule,electrocardiography,enoxaparin,female,hemorrhage,heparin,hospitalization,humans,male,middle aged,myocardial infarction,polysaccharides,stroke,treatment outcome
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Norwich Clinical Trials Unit Faculty of Medicine and Health Sciences > Research Groups > Cardiovascular and Metabolic Health Faculty of Medicine and Health Sciences > Research Groups > Public Health and Health Services Research (former - to 2023)
Depositing User:	Pure Connector
Date Deposited:	06 Jan 2014 15:20
Last Modified:	03 Nov 2022 15:35
URI:	https://ueaeprints.uea.ac.uk/id/eprint/46265
DOI:	10.1161/CIRCULATIONAHA.108.789479

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