4D super-resolution microscopy with conventional fluorophores and single wavelength excitation in optically thick cells and tissues

Baddeley, David, Crossman, David, Rossberger, Sabrina, Cheyne, Juliette E., Montgomery, Johanna M., Jayasinghe, Isuru D., Cremer, Christoph, Cannell, Mark B. and Soeller, Christian (2011) 4D super-resolution microscopy with conventional fluorophores and single wavelength excitation in optically thick cells and tissues. PLoS One, 6 (5). ISSN 1932-6203

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Abstract

Optical super-resolution imaging of fluorescently stained biological samples is rapidly becoming an important tool to investigate protein distribution at the molecular scale. It is therefore important to develop practical super-resolution methods that allow capturing the full three-dimensional nature of biological systems and also can visualize multiple protein species in the same sample.

Item Type:	Article
Additional Information:	© 2011 Baddeley et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Uncontrolled Keywords:	animals,cells, cultured,cyclic amp,humans,microscopy, fluorescence,models, theoretical,myocytes, cardiac,rats,succinimides
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Norwich Clinical Trials Unit
Depositing User:	Pure Connector
Date Deposited:	06 Jan 2014 14:56
Last Modified:	24 Oct 2022 05:34
URI:	https://ueaeprints.uea.ac.uk/id/eprint/46188
DOI:	10.1371/journal.pone.0020645

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