Apoptosis regulators Fau and Bcl-G are down-regulated in prostate cancer

Pickard, Mark R, Edwards, Sandra E, Cooper, Colin S and Williams, Gwyn T (2010) Apoptosis regulators Fau and Bcl-G are down-regulated in prostate cancer. The Prostate, 70 (14). pp. 1513-23. ISSN 1097-0045

Full text not available from this repository. (Request a copy)

Abstract

The molecular control of cell death through apoptosis is compromised in prostate cancer cells, resulting in inappropriate cell survival and resistance to cytotoxic therapy. Reduced expression of the functionally connected apoptosis-regulators and candidate tumor suppressors Fau and Bcl-G has recently been implicated in oncogenesis in other tissues. The present study examines the hypothesis that reduced expression of these genes may be involved in prostate cancer.

Item Type: Article
Additional Information: (c) 2010 Wiley-Liss, Inc.
Uncontrolled Keywords: aged,apoptosis,cell line, tumor,cell survival,gene expression regulation, neoplastic,genes, bcl-1,humans,male,middle aged,neoplasm staging,prostate,prostatic hyperplasia,prostatic neoplasms,proto-oncogene proteins c-bcl-2,rna interference,rna, messenger,rna, small interfering,reverse transcriptase polymerase chain reaction,ribosomal proteins,ultraviolet rays
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Depositing User: Pure Connector
Date Deposited: 06 Jan 2014 15:20
Last Modified: 24 Jul 2019 19:28
URI: https://ueaeprints.uea.ac.uk/id/eprint/46129
DOI: 10.1002/pros.21186

Actions (login required)

View Item View Item