Apoptosis regulators Fau and Bcl-G are down-regulated in prostate cancer

Pickard, Mark R, Edwards, Sandra E, Cooper, Colin S ORCID: https://orcid.org/0000-0003-2013-8042 and Williams, Gwyn T (2010) Apoptosis regulators Fau and Bcl-G are down-regulated in prostate cancer. The Prostate, 70 (14). pp. 1513-23. ISSN 1097-0045

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Abstract

The molecular control of cell death through apoptosis is compromised in prostate cancer cells, resulting in inappropriate cell survival and resistance to cytotoxic therapy. Reduced expression of the functionally connected apoptosis-regulators and candidate tumor suppressors Fau and Bcl-G has recently been implicated in oncogenesis in other tissues. The present study examines the hypothesis that reduced expression of these genes may be involved in prostate cancer.

Item Type:	Article
Additional Information:	(c) 2010 Wiley-Liss, Inc.
Uncontrolled Keywords:	aged,apoptosis,cell line, tumor,cell survival,gene expression regulation, neoplastic,genes, bcl-1,humans,male,middle aged,neoplasm staging,prostate,prostatic hyperplasia,prostatic neoplasms,proto-oncogene proteins c-bcl-2,rna interference,rna, messenger,rna, small interfering,reverse transcriptase polymerase chain reaction,ribosomal proteins,ultraviolet rays,sdg 3 - good health and well-being ,/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Cancer Studies
Depositing User:	Pure Connector
Date Deposited:	06 Jan 2014 15:20
Last Modified:	24 Oct 2022 05:31
URI:	https://ueaeprints.uea.ac.uk/id/eprint/46129
DOI:	10.1002/pros.21186

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