Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array

Eeles, Rosalind A, Olama, Ali Amin Al, Benlloch, Sara, Saunders, Edward J, Leongamornlert, Daniel A, Tymrakiewicz, Malgorzata, Ghoussaini, Maya, Luccarini, Craig, Dennis, Joe, Jugurnauth-Little, Sarah, Dadaev, Tokhir, Neal, David E, Hamdy, Freddie C, Donovan, Jenny L, Muir, Ken, Giles, Graham G, Severi, Gianluca, Wiklund, Fredrik, Gronberg, Henrik, Haiman, Christopher A, Schumacher, Fredrick, Henderson, Brian E, Le Marchand, Loic, Lindstrom, Sara, Kraft, Peter, Hunter, David J, Gapstur, Susan, Chanock, Stephen J, Berndt, Sonja I, Albanes, Demetrius, Andriole, Gerald, Schleutker, Johanna, Weischer, Maren, Canzian, Federico, Riboli, Elio, Key, Tim J, Travis, Ruth C, Campa, Daniele, Ingles, Sue A, John, Esther M, Hayes, Richard B, Pharoah, Paul D P, Pashayan, Nora, Khaw, Kay-Tee, Stanford, Janet L, Ostrander, Elaine A, Signorello, Lisa B, Thibodeau, Stephen N, Schaid, Dan and Cooper, Colin S ORCID: https://orcid.org/0000-0003-2013-8042 and COGS–Cancer Research UK GWAS–ELLIPSE (part of GAME-ON) Initiative (2013) Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array. Nature Genetics, 45 (4). 385-91, 391e1-2. ISSN 1061-4036

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Abstract

Prostate cancer is the most frequently diagnosed cancer in males in developed countries. To identify common prostate cancer susceptibility alleles, we genotyped 211,155 SNPs on a custom Illumina array (iCOGS) in blood DNA from 25,074 prostate cancer cases and 24,272 controls from the international PRACTICAL Consortium. Twenty-three new prostate cancer susceptibility loci were identified at genome-wide significance (P

Item Type:	Article
Uncontrolled Keywords:	case-control studies,cooperative behavior,genetic loci,genetic predisposition to disease,genome-wide association study,genotype,humans,male,meta-analysis as topic,oligonucleotide array sequence analysis,polymorphism, single nucleotide,prostatic neoplasms,risk factors,sdg 3 - good health and well-being ,/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Cancer Studies
Depositing User:	Pure Connector
Date Deposited:	20 Jan 2014 15:58
Last Modified:	03 Nov 2022 15:34
URI:	https://ueaeprints.uea.ac.uk/id/eprint/46117
DOI:	10.1038/ng.2560

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