Anthracycline-based chemotherapy as first-line treatment in adults with malignant posttransplant lymphoproliferative disorder after solid organ transplantation

Taylor, Anna L., Bowles, Kristian M. ORCID: https://orcid.org/0000-0003-1334-4526, Callaghan, Christopher J., Wimperis, Jenny Z., Grant, John W., Marcus, Robert E. and Bradley, J. Andrew (2006) Anthracycline-based chemotherapy as first-line treatment in adults with malignant posttransplant lymphoproliferative disorder after solid organ transplantation. Transplantation, 82 (3). pp. 375-381. ISSN 0041-1337

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Abstract

Recommended first-line treatment for posttransplant lymphoproliferative disorder (PTLD) is reduction in immunosuppressive therapy, irrespective of histopathological type. Second-line treatment with chemotherapy is generally reserved for tumors that fail to respond to reduced immunosuppression. In view of the similarities between monomorphic PTLD and non-Hodgkin's lymphoma in the general population, our policy is to treat monomorphic PTLD with anthracycline-based chemotherapy as first-line treatment.

Item Type: Article
Uncontrolled Keywords: adolescent,adult,aged,anthracyclines,biopsy,female,humans,kidney transplantation,lymphoma,lymphoproliferative disorders,male,middle aged,survival rate,time factors,treatment outcome
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Depositing User: Pure Connector
Date Deposited: 16 Dec 2013 15:12
Last Modified: 13 Aug 2022 19:38
URI: https://ueaeprints.uea.ac.uk/id/eprint/45984
DOI: 10.1097/01.tp.0000228906.31675.fb

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