Anthracycline-based chemotherapy as first-line treatment in adults with malignant posttransplant lymphoproliferative disorder after solid organ transplantation

Taylor, Anna L., Bowles, Kristian M., Callaghan, Christopher J., Wimperis, Jenny Z., Grant, John W., Marcus, Robert E. and Bradley, J. Andrew (2006) Anthracycline-based chemotherapy as first-line treatment in adults with malignant posttransplant lymphoproliferative disorder after solid organ transplantation. Transplantation, 82 (3). pp. 375-381. ISSN 0041-1337

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Abstract

Recommended first-line treatment for posttransplant lymphoproliferative disorder (PTLD) is reduction in immunosuppressive therapy, irrespective of histopathological type. Second-line treatment with chemotherapy is generally reserved for tumors that fail to respond to reduced immunosuppression. In view of the similarities between monomorphic PTLD and non-Hodgkin's lymphoma in the general population, our policy is to treat monomorphic PTLD with anthracycline-based chemotherapy as first-line treatment.

Item Type:	Article
Uncontrolled Keywords:	adolescent,adult,aged,anthracyclines,biopsy,female,humans,kidney transplantation,lymphoma,lymphoproliferative disorders,male,middle aged,survival rate,time factors,treatment outcome
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Cancer Studies
Depositing User:	Pure Connector
Date Deposited:	16 Dec 2013 15:12
Last Modified:	06 Feb 2025 04:42
URI:	https://ueaeprints.uea.ac.uk/id/eprint/45984
DOI:	10.1097/01.tp.0000228906.31675.fb

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