Anthracycline-based chemotherapy as first-line treatment in adults with malignant posttransplant lymphoproliferative disorder after solid organ transplantation

Taylor, Anna L., Bowles, Kristian M. ORCID: https://orcid.org/0000-0003-1334-4526, Callaghan, Christopher J., Wimperis, Jenny Z., Grant, John W., Marcus, Robert E. and Bradley, J. Andrew (2006) Anthracycline-based chemotherapy as first-line treatment in adults with malignant posttransplant lymphoproliferative disorder after solid organ transplantation. Transplantation, 82 (3). pp. 375-381. ISSN 0041-1337

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Abstract

Recommended first-line treatment for posttransplant lymphoproliferative disorder (PTLD) is reduction in immunosuppressive therapy, irrespective of histopathological type. Second-line treatment with chemotherapy is generally reserved for tumors that fail to respond to reduced immunosuppression. In view of the similarities between monomorphic PTLD and non-Hodgkin's lymphoma in the general population, our policy is to treat monomorphic PTLD with anthracycline-based chemotherapy as first-line treatment.

Item Type:	Article
Uncontrolled Keywords:	adolescent,adult,aged,anthracyclines,biopsy,female,humans,kidney transplantation,lymphoma,lymphoproliferative disorders,male,middle aged,survival rate,time factors,treatment outcome
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Cancer Studies
Depositing User:	Pure Connector
Date Deposited:	16 Dec 2013 15:12
Last Modified:	24 Oct 2022 05:28
URI:	https://ueaeprints.uea.ac.uk/id/eprint/45984
DOI:	10.1097/01.tp.0000228906.31675.fb

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