Vitamin D and respiratory health

Hughes, David A. and Norton, Rosemary (2009) Vitamin D and respiratory health. Clinical & Experimental Immunology, 158 (1). pp. 20-25. ISSN 1365-2249

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Abstract

Vitamin D is now known to be of physiological importance outside of bone health and calcium homeostasis, and there is mounting evidence that it plays a beneficial role in the prevention and/or treatment of a wide range of diseases. In this brief review the known effects of vitamin D on immune function are described in relation to respiratory health. Vitamin D appears capable of inhibiting pulmonary inflammatory responses while enhancing innate defence mechanisms against respiratory pathogens. Population-based studies showing an association between circulating vitamin D levels and lung function provide strong justification for randomized controlled clinical trials of vitamin D supplementation in patients with respiratory diseases to assess both efficacy and optimal dosage.

Item Type: Article
Faculty \ School: Faculty of Science > School of Pharmacy
UEA Research Groups: Faculty of Science > Research Groups > Innovations in Pharmacy Education
Depositing User: Pure Connector
Date Deposited: 06 Jan 2014 14:42
Last Modified: 09 Aug 2023 13:30
URI: https://ueaeprints.uea.ac.uk/id/eprint/45951
DOI: 10.1111/j.1365-2249.2009.04001.x

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