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ToolsTodd, Jonathan D., Wexler, Margaret, Sawers, Gary, Yeoman, Kay H., Poole, Philip S. and Johnston, Andrew W. B. (2003) RirA, an iron-responsive regulator in the symbiotic bacterium Rhizobium leguminosarum. Microbiology, 148 (12). pp. 4059-4071. ISSN 1350-0872
Full text not available from this repository. (Request a copy)Abstract
Mutations in a Rhizobium leguminosarum gene, rirA (rhizobial iron regulator), caused high-level, constitutive expression of at least eight operons whose transcription is normally Fe-responsive and whose products are involved in the synthesis or uptake of siderophores, or in the uptake of haem or of other iron sources. Close homologues of RirA exist in other rhizobia and in the pathogen Brucella; many other bacteria have deduced proteins with more limited sequence similarity. None of these homologues had been implicated in Fe-mediated gene regulation. Transcription of rirA itself is about twofold higher in cells grown in Fe-replete than in Fe-deficient growth media. Mutations in rirA reduced growth rates in Fe-replete and -depleted medium, but did not appear to affect symbiotic N fixation.
| Item Type: | Article |
|---|---|
| Faculty \ School: | Faculty of Science > School of Biological Sciences |
| UEA Research Groups: | Faculty of Science > Research Groups > Molecular Microbiology Faculty of Social Sciences > Research Groups > Research in Mathematics Education |
| Related URLs: | |
| Depositing User: | EPrints Services |
| Date Deposited: | 01 Oct 2010 13:36 |
| Last Modified: | 24 Sep 2024 10:13 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/459 |
| DOI: | 10.1099/00221287-148-12-4059 |
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