Population variation in glial fibrillary acidic protein levels in brain ageing:relationship to Alzheimer-type pathology and dementia

Wharton, S B, O'Callaghan, J P, Savva, G M, Nicoll, J A R, Matthews, F, Simpson, J E, Forster, G, Shaw, P J, Brayne, C and Ince, P G and MRC Cognitive Function and Ageing Neuropathology Study Group (2009) Population variation in glial fibrillary acidic protein levels in brain ageing:relationship to Alzheimer-type pathology and dementia. Dementia and Geriatric Cognitive Disorders, 27 (5). pp. 465-473. ISSN 1421-9824

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Abstract

The cellular pathology of astrocytes in brain ageing and their role in modulating the brain's response to neurodegenerative pathology remain incompletely understood.

Item Type:	Article
Uncontrolled Keywords:	aged,aging,alzheimer disease,amyloid beta-peptides,apolipoprotein e4,astrocytes,brain,brain chemistry,cohort studies,dementia,disease progression,enzyme-linked immunosorbent assay,female,genotype,glial fibrillary acidic protein,gliosis,humans,immunohistochemistry,male
Faculty \ School:
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Health in Later Life (former - to 2017) Faculty of Science > Research Groups > Norwich Epidemiology Centre Faculty of Medicine and Health Sciences > Research Groups > Norwich Epidemiology Centre
Depositing User:	Pure Connector
Date Deposited:	02 Dec 2013 14:28
Last Modified:	14 Oct 2025 17:32
URI:	https://ueaeprints.uea.ac.uk/id/eprint/44944
DOI:	10.1159/000217729

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