Complete Versus culprit-Lesion only PRimary PCI Trial (CVLPRIT):a multicentre trial testing management strategies when multivessel disease is detected at the time of primary PCI: rationale and design

Kelly, Damian J, McCann, Gerald P, Blackman, Daniel, Curzen, Nicholas P, Dalby, Miles, Greenwood, John P, Fairbrother, Kathryn, Shipley, Lorraine, Kelion, Andrew, Heatherington, Simon, Khan, Jamal N, Nazir, Sheraz, Alahmar, Albert, Flather, Marcus, Swanton, Howard, Schofield, Peter, Gunning, Mark, Hall, Roger and Gershlick, Anthony H (2013) Complete Versus culprit-Lesion only PRimary PCI Trial (CVLPRIT):a multicentre trial testing management strategies when multivessel disease is detected at the time of primary PCI: rationale and design. Eurointervention, 8 (10). pp. 1190-8. ISSN 1774-024X

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Abstract

Primary percutaneous coronary intervention (PPCI) is the preferred strategy for acute ST-segment elevation myocardial infarction (STEMI), with evidence of improved clinical outcomes compared to fibrinolytic therapy. However, there is no consensus on how best to manage multivessel coronary disease detected at the time of PPCI, with little robust data on best management of angiographically significant stenoses detected in non-infarct-related (N-IRA) coronary arteries. CVLPRIT will determine the optimal management of N-IRA lesions detected during PPCI.

Item Type: Article
Uncontrolled Keywords: prospective studies,endpoint determination,humans,percutaneous coronary intervention,research design,coronary artery disease
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups: Faculty of Medicine and Health Sciences > Research Groups > Cardiovascular and Metabolic Health
Faculty of Medicine and Health Sciences > Research Groups > Norwich Clinical Trials Unit
Faculty of Medicine and Health Sciences > Research Groups > Public Health and Health Services Research (former - to 2023)
Depositing User: Pure Connector
Date Deposited: 11 Nov 2013 13:32
Last Modified: 24 Oct 2022 05:00
URI: https://ueaeprints.uea.ac.uk/id/eprint/44356
DOI: 10.4244/EIJV8I10A183

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