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ToolsRedshaw, Carl, Watkins, Scott, Humphrey, Simon M., Bulman Page, Philip C., Ashby, Shane, Chao, Yimin, Herbert, Christopher J. and Mueller, Anja (2013) Rhenium(I) phenanthrolines bearing electron withdrawing CF3 substituents: synthesis, characterization and biological evaluation. RSC Advances, 3 (46). pp. 23963-23966. ISSN 2046-2069
Full text not available from this repository. (Request a copy)Abstract
Rhenium(I) tricarbonyl complexes bearing a 2,4,7,9-tetraphenylphenanthroline ligand, where the 2,9-phenyl groups have either meta- or para-CF3 groups, have been screened against a selection of cell lines. The meta derivative shows anticancer activity against HeLa and A549 cell lines, whereas the para derivative causes proliferation of HL-60 cells, whilst showing toxicity towards A549 cells.
| Item Type: | Article |
|---|---|
| Faculty \ School: | Faculty of Science > School of Chemistry (former - to 2024) Faculty of Science > School of Pharmacy (former - to 2024) |
| UEA Research Groups: | Faculty of Science > Research Groups > Synthetic Chemistry (former - to 2017) Faculty of Science > Research Groups > Physical and Analytical Chemistry (former - to 2017) Faculty of Science > Research Groups > Pharmaceutical Cell Biology (former - to 2017) Faculty of Science > Research Groups > Chemistry of Materials and Catalysis Faculty of Science > Research Groups > Molecular and Tissue Pharmacology Faculty of Science > Research Groups > Energy Materials Laboratory |
| Depositing User: | Pure Connector |
| Date Deposited: | 06 Nov 2013 12:22 |
| Last Modified: | 28 Mar 2025 05:24 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/44275 |
| DOI: | 10.1039/c3ra43207f |
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