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Magnusson, Johannes Pall, Khan, Adnan, Pasparakis, George, Saeed, Aram Omer 
ORCID: https://orcid.org/0000-0003-2903-5875, Wang, Wenxin and Alexander, Cameron
(2008)
Ion-sensitive “isothermal” responsive polymers prepared in water.
Journal of the American Chemical Society, 130 (33).
pp. 10852-10853.
ISSN 0002-7863
Abstract
Ion-sensitive responsive polymers are prepared under fully aqueous conditions using controlled radical polymerization. Variations in comonomer content and sequence lead to temperature and salt-dependent solution behavior, with cloud-points ranging by ±40 °C following addition of Hofmeister series salts. A “hybrid” block copolymer, composed of a statistical sequence of monomers tipped with a hydrophilic block, formed stable micelle-like assemblies that exhibited burst release of an encapsulated model drug in response to addition of a kosmotrope, Na2SO4, at room temperature.
| Item Type: | Article |
|---|---|
| Faculty \ School: | Faculty of Science > School of Pharmacy |
| UEA Research Groups: | Faculty of Science > Research Groups > Drug Delivery and Pharmaceutical Materials (former - to 2017) Faculty of Science > Research Groups > Pharmaceutical Materials and Soft Matter |
| Depositing User: | Pure Connector |
| Date Deposited: | 23 Oct 2013 10:34 |
| Last Modified: | 04 Jul 2023 16:30 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/43821 |
| DOI: | 10.1021/ja802609r |
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