The reverse of polymer degradation: in situ crosslinked gel formation through disulfide cleavage

Saeed, Aram O., Newland, Ben, Pandit, Abhay and Wang, Wenxin (2012) The reverse of polymer degradation: in situ crosslinked gel formation through disulfide cleavage. Chemical Communications, 48 (4). pp. 585-587. ISSN 1359-7345

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Abstract

In contrast to the usual inclusion of disulfide bonds within a polymer structure to facilitate bio-degradation, we have designed a self-curing “one pot” hyperbranched polymer capable of forming crosslinked gels under reducing conditions abundant in tumoural tissue.

Item Type:	Article
Faculty \ School:	Faculty of Science > School of Pharmacy (former - to 2024)
UEA Research Groups:	Faculty of Science > Research Groups > Drug Delivery and Pharmaceutical Materials (former - to 2017) Faculty of Science > Research Groups > Pharmaceutical Materials and Soft Matter
Depositing User:	Pure Connector
Date Deposited:	23 Oct 2013 11:46
Last Modified:	14 Jul 2025 13:30
URI:	https://ueaeprints.uea.ac.uk/id/eprint/43813
DOI:	10.1039/c1cc16538k

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