The reverse of polymer degradation: in situ crosslinked gel formation through disulfide cleavage

Saeed, Aram O. ORCID: https://orcid.org/0000-0003-2903-5875, Newland, Ben, Pandit, Abhay and Wang, Wenxin (2012) The reverse of polymer degradation: in situ crosslinked gel formation through disulfide cleavage. Chemical Communications, 48 (4). pp. 585-587. ISSN 1359-7345

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Abstract

In contrast to the usual inclusion of disulfide bonds within a polymer structure to facilitate bio-degradation, we have designed a self-curing “one pot” hyperbranched polymer capable of forming crosslinked gels under reducing conditions abundant in tumoural tissue.

Item Type: Article
Faculty \ School: Faculty of Science > School of Pharmacy (former - to 2024)
UEA Research Groups: Faculty of Science > Research Groups > Drug Delivery and Pharmaceutical Materials (former - to 2017)
Faculty of Science > Research Groups > Pharmaceutical Materials and Soft Matter
Depositing User: Pure Connector
Date Deposited: 23 Oct 2013 11:46
Last Modified: 24 Sep 2024 10:42
URI: https://ueaeprints.uea.ac.uk/id/eprint/43813
DOI: 10.1039/c1cc16538k

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