Tools
ToolsVan den Bossche, Jeroen, Al-Jamal, Wafa' T, Tian, Bowen, Nunes, Antonio, Fabbro, Chiara, Bianco, Alberto, Prato, Maurizio and Kostarelos, Kostas (2010) Efficient receptor-independent intracellular translocation of aptamers mediated by conjugation to carbon nanotubes. Chemical communications (Cambridge, England), 46 (39). pp. 7379-7381. ISSN 1364-548X
Full text not available from this repository.Abstract
We have covalently grafted aptamers onto carboxylated carbon nanotubes to design a novel vector system that can easily translocate into the cytosol of different cell types independent of receptor-mediated uptake. We propose the use of carbon nanotubes for the efficient intracellular delivery of biologically active aptamers for potential therapeutic applications.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | microscopy, electron, transmission,base sequence,electrophoresis, polyacrylamide gel,humans,dna primers,aptamers, nucleotide,biological transport,cell line, tumor,receptors, cell surface,nanotubes, carbon |
| Faculty \ School: | Faculty of Science > School of Pharmacy |
| UEA Research Groups: | Faculty of Science > Research Groups > Drug Delivery and Pharmaceutical Materials (former - to 2017) |
| Depositing User: | Pure Connector |
| Date Deposited: | 05 Oct 2013 00:55 |
| Last Modified: | 24 Oct 2022 04:43 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/43578 |
| DOI: | 10.1039/c0cc02092c |
Actions (login required)
 |
View Item |