Experimental approaches for gene regulatory network construction: The chick as a model system

Streit, Andrea, Tambalo, Monica, Chen, Jingchen, Grocott, Timothy ORCID: https://orcid.org/0000-0002-6321-401X, Anwar, Maryam, Sosinsky, Alona and Stern, Claudio D. (2013) Experimental approaches for gene regulatory network construction: The chick as a model system. genesis, 51 (5). pp. 296-310. ISSN 1526-954X

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Abstract

Setting up the body plan during embryonic development requires the coordinated action of many signals and transcriptional regulators in a precise temporal sequence and spatial pattern. The last decades have seen an explosion of information describing the molecular control of many developmental processes. The next challenge is to integrate this information into logic “wiring diagrams” that visualize gene actions and outputs, have predictive power and point to key control nodes. Here, we provide an experimental workflow on how to construct gene regulatory networks using the chick as model system.

Item Type:	Article
Faculty \ School:	Faculty of Science > School of Biological Sciences
UEA Research Groups:	Faculty of Science > Research Groups > Cells and Tissues
Depositing User:	Pure Connector
Date Deposited:	10 Jul 2013 08:46
Last Modified:	04 Mar 2024 16:49
URI:	https://ueaeprints.uea.ac.uk/id/eprint/42962
DOI:	10.1002/dvg.22359

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