Can non-contact SIAscopy be used in the diagnosis and quantification of pigmentary skin changes associated with photodamage?

Walls, Joseph (2012) Can non-contact SIAscopy be used in the diagnosis and quantification of pigmentary skin changes associated with photodamage? Doctoral thesis, University of East Anglia.

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Abstract

Can non-contact SIAscopy be used in the diagnosis and quantification of
pigmentary skin changes associated with photodamage?
Introduction
Non-contact SIAscopy is a new imaging technique where a standard polarised
photographic image of the skin is decomposed to produce independent colour,
blood and melanin images using SIAscopy (a form of reflectance spectroscopy).
Photodamage is a product of the physiological changes caused by
chronic sun exposure on the skin. Measuring the extent of photodamage has
always been difficult, with most analysis requiring subjective user interpretation
of results. No one available method appears better at clearly identifying and
quantifying photodamage within the skin and no truly objective method exists
which enables automatic measurement of these characteristics without expert
evaluation.
Methods and results
1140 images of skin of various ages and levels of damage were acquired using
standard digital colour photography obtained through crossed polarising filters.
The sample was split into a model and test set and analysis algorithms were
employed to quantify features including dyspigmentation, sallowness, erythema
and vessel dilation. Relevant features were isolated and the relationship with
age was determined using linear regression. From this a predictive skin photodamage
age was generated and tested with a sample set of images.
Conclusions
Specific pigmentary characteristic of photodamage can be identified and quantified
using non-contact SIAscopy. It is an independent, repeatable, robust and
inexpensive method of assessing the level of photodamage from a standard
digital photograph and the results can be used to identify individuals most at
risk of developing skin cancers.

Item Type: Thesis (Doctoral)
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Depositing User: Mia Reeves
Date Deposited: 14 May 2013 11:47
Last Modified: 14 May 2013 11:47
URI: https://ueaeprints.uea.ac.uk/id/eprint/42386
DOI:

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