Trends in childhood tuberculosis in Zambia: A situation analysis

Kapata, Nathan, Chanda-Kapata, Pascalina, O'Grady, Justin, Bates, Matthew, Mwaba, Peter, Janssen, Saskia, Marais, Ben, Cobelens, Frank, Grobusch, Martin and Zumla, Alimuddin (2013) Trends in childhood tuberculosis in Zambia: A situation analysis. Journal of Tropical Pediatrics, 59 (2). pp. 134-139. ISSN 1465-3664

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Abstract

Objectives: To ascertain childhood tuberculosis (TB) trends, human immunodeficiency virus (HIV) co-infection rates and multi-drug resistant TB (MDR-TB) prevalence rates in Zambia. Methods: A retrospective review of Zambian annual TB notification data and National TB Programme reports for a 7 year period (2004–2011). TB trends were stratified by age and HIV status. Results: The total number of children notified during this period with all forms of TB was 40 976. A total of 2670 of 40 976 (6%) were smear-positive cases. Notification rates of all forms of childhood TB show a decline in trends from 135 per 100 000 population in 2004, to 69 per 100 000 population in 2011. Conclusions: Childhood TB is an important but neglected problem in Zambia highlighted by the fact that no data exists on HIV co-infection and MDR-TB. Strengthening of the National TB Programme and diagnostics services/algorithms are required to accurately define the TB burden, HIV co-infection and MDR-TB rates in children in Zambia.

Item Type:	Article
Uncontrolled Keywords:	sdg 3 - good health and well-being ,/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Medical Microbiology (former - to 2018)
Depositing User:	Sophie Buckingham
Date Deposited:	05 Mar 2013 10:24
Last Modified:	02 Feb 2024 01:34
URI:	https://ueaeprints.uea.ac.uk/id/eprint/41793
DOI:	10.1093/tropej/fms065

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