Activity of carbapenems with ME1071 (disodium 2,3-diethylmaleate) against Enterobacteriaceae and Acinetobacter spp. with carbapenemases, including NDM enzymes

Livermore, David M., Mushtaq, Shazad, Morinaka, Akihiro, Ida, Takashi, Maebashi, Kazunori and Hope, Russell (2013) Activity of carbapenems with ME1071 (disodium 2,3-diethylmaleate) against Enterobacteriaceae and Acinetobacter spp. with carbapenemases, including NDM enzymes. Journal of Antimicrobial Chemotherapy, 68 (1). pp. 153-158. ISSN 0305-7453

Full text not available from this repository. (Request a copy)

Abstract

ME1071 is a maleic acid that inhibits metallo-β-lactamases (MBLs). We examined its ability to potentiate different carbapenems against MBL-producing Enterobacteriaceae in relation to its inhibition kinetics.

Item Type:	Article
Uncontrolled Keywords:	acinetobacter,bacterial proteins,carbapenems,drug synergism,enterobacteriaceae,enzyme inhibitors,humans,maleates,microbial sensitivity tests,beta-lactamases
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Public Health and Health Services Research (former - to 2023) Faculty of Medicine and Health Sciences > Research Groups > Epidemiology and Public Health
Depositing User:	Sophie Buckingham
Date Deposited:	05 Mar 2013 10:49
Last Modified:	06 Feb 2025 01:24
URI:	https://ueaeprints.uea.ac.uk/id/eprint/41719
DOI:	10.1093/jac/dks350

Actions (login required)

View Item